Topoisomerase I antibody (AA 50-99)

Catalog No. ABIN6747303

The Rabbit Polyclonal anti-Topoisomerase I antibody has been validated for WB. It is suitable to detect Topoisomerase I in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Pig, Bat, Hamster and Monkey.

Quick Overview for Topoisomerase I antibody (AA 50-99) (ABIN6747303)

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Pig, Bat, Hamster, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Topoisomerase I antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Topoisomerase I Antibody

Binding Specificity: AA 50-99

Specificity: Human TOP1 / Topoisomerase I

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Bovine, Rabbit, Pig, Guinea pig (100%) Rat, Chicken (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa50-99 of human TOP1 (P11387, NP_003277). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig (100%), Turkey, Zebra finch, Chicken (92%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for Topoisomerase I

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Alternative Name: TOP1 / Topoisomerase I

Background: Name/Gene ID: TOP1
Family: Topoisomerase

Synonyms: TOP1, DNA topoisomerase I, DNA topoisomerase 1, TOPI, Topoisomerase (DNA) I, Topoisomerase I, Type I DNA topoisomerase

Gene ID: 7150

NCBI Accession: NP_003277

UniProt: P11387

Pathways: Caspase Cascade in Apoptosis, Stem Cell Maintenance